PF-03758309 (hydrochloride)

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For R&D use only.

Catalog NO.：A900339
CAS No. : 1279034-84-2
Molecular Formula：C₂₅H₃₁ClN₈Os
Molecular Weight： 527.09

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Product Details

CAS Number	1279034-84-2	Appearance
Catalog Number	A900339	MDL Number
Molecular Formula	C₂₅H₃₁ClN₈Os	Molecular Weight	527.09
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(S)-N-(2-(dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno[3,2-d]pyrimidin-4-yl)amino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide hydrochloride
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

PF-3758309, also known as PF-03758309, is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PAK4 inhibitor PF-03758309 binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.

898044-15-0 (free base)

1279034-84-2 (HCl)

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