Linsitinib
- Catalog NO.:A857471
- CAS No. : 867160-71-2
- Molecular Formula:C26H23N5O
- Molecular Weight: 421.49
Note*
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3. The price does not include shipping and bank charges.
Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 867160-71-2 | Appearance | Light yellow powder |
Catalog Number | A857471 | MDL Number | MFCD12912153 |
Molecular Formula | C26H23N5O | Molecular Weight | 421.49 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | OSI-906;cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
Linsitinib, also known as OSI-906, is a n orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis. |