Telotristat etiprate

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For R&D use only.

Catalog NO.：A894321
CAS No. : 1137608-69-5
Molecular Formula：C₃₆H₃₅ClF₃N₇O₆
Molecular Weight： 754.16

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Product Details

CAS Number	1137608-69-5	Appearance
Catalog Number	A894321	MDL Number	MFCD22741520
Molecular Formula	C₃₆H₃₅ClF₃N₇O₆	Molecular Weight	754.16
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate hippurate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Telotristat etiprate, its free base also known as LX1606 or LX1032, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor . Telotristat etiprate has activity in controlling diarrhea associated with carcinoid syndrome. LX1606 acts by inhibiting the enzyme tryptophan hydoxylase (TPH) and reduces serotonin production both inside and outside the GI tract without affecting brain serotonin levels. TPH is the rate-limiting enzyme involved in serotonin biosynthesis and is present in metastatic carcinoid tumor cells.

1137608-69-5 (etiprate)

1033805-22-9 (ethyl)

1033805-28-5 (acid)

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