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Cilastatin sodium

  • Catalog NO.:A840047
  • CAS No. : 81129-83-1
  • Molecular Formula:C16H25N2NaO5S
  • Molecular Weight: 380.43
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Product Details

CAS Number 81129-83-1 Appearance
Catalog Number A840047 MDL Number
Molecular Formula C16H25N2NaO5S Molecular Weight 380.43
Boiling Point Melting Point
Flash Point Density
Synonyms MK 0791;sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate;(2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid sodium salt
Storage Condition Store in a tightly closed container,in a cool and dry place

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Description

Dipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a Ki value of 0.11 μM. Inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.

81129-83-1 (sodium)

82009-34-5 (free acid)

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Cilastatin sodium
MK 0791;sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate;(2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid sodium salt