PIK-294
- Catalog NO.:A860932
- CAS No. : 900185-02-6
- Molecular Formula:C28H23N7O2
- Molecular Weight: 489.53
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 900185-02-6 | Appearance | Crystalline solid |
Catalog Number | A860932 | MDL Number | MFCD17019338 |
Molecular Formula | C28H23N7O2 | Molecular Weight | 489.53 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Danger | UN Number | 2811 |
Hazard Statements | H301 | Class | 6.1 |
Precautionary Statements | P301+P310+P330 | Packing Group | Ⅲ |
Description
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110δ with an IC50 value of 10 nM compared to IC50 values of 10 μM, 490 nM and 160 nM for PI3Kα/β/γ, respectively. PIK-294 has been used to help distinguish the unique roles of the various PI3-K isoforms. PIK-294 inhibited both chemokinetic and chemotactic CXCL8-induced migration. |