I-BET151
- Catalog NO.:A857561
- CAS No. : 1300031-49-5
- Molecular Formula:C23H21N5O3
- Molecular Weight: 415.16
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1300031-49-5 | Appearance | White powder |
Catalog Number | A857561 | MDL Number | MFCD22124472 |
Molecular Formula | C23H21N5O3 | Molecular Weight | 415.16 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | GSK1210151A;7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H317-H319 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
GSK1210151A, also known as I-BET151, is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. I-BET151 ( GSK1210151A ) shows good oral bioavailability in both the rat and minipig as well as demonstrating efficient suppression of bacterial induced inflammation and sepsis in a murine in vivo endotoxaemia model. |