5-Methyl-Uridine-5'-Monophosphate, Disodium Salt

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For R&D use only.

Catalog NO.：A905912
CAS No. : 117309-80-5
Molecular Formula：C₁₀H₁₃N₂Na₂O₉P
Molecular Weight： 382.17

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Product Details

CAS Number	117309-80-5	Appearance
Catalog Number	A905912	MDL Number
Molecular Formula	C₁₀H₁₃N₂Na₂O₉P	Molecular Weight	382.17
Boiling Point		Melting Point
Flash Point		Density
Synonyms	sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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