Luminespib
- Catalog NO.:A9562
- CAS No. : 747412-49-3
- Molecular Formula:C26H31N3O5
- Molecular Weight: 465.54
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 747412-49-3 | Appearance | White to off-white solid |
Catalog Number | A9562 | MDL Number | MFCD14635361 |
Molecular Formula | C26H31N3O5 | Molecular Weight | 465.54 |
Boiling Point | 640.1°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | NVP-AUY922;5-[2,4-Dihydroxy-5-isopropylphenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines. |