Desfesoterodine

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For R&D use only.

Catalog NO.：A879440
CAS No. : 207679-81-0
Molecular Formula：C₂₂H₃₁NO₂
Molecular Weight： 341.49

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Product Details

CAS Number	207679-81-0	Appearance
Catalog Number	A879440	MDL Number	MFCD09264524
Molecular Formula	C₂₂H₃₁NO₂	Molecular Weight	341.49
Boiling Point	490.721°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	(R)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Desfesoterodine, also known as PNU-200577, is a major pharmacologically active metabolite of tolterodine, a new muscarinic receptor antagonist intended for the treatment of an overactive bladder. In vitro, PNU-200577 produced a competitive and concentration-dependent inhibition of carbachol-induced contraction of guinea-pig isolated urinary bladder strips (KB = 0.84 nM; pA2 = 9.14). In vivo, PNU-200577 was significantly more potent at inhibiting acetylcholine-induced urinary bladder contraction than electrically induced salivation in the anaesthetised cat (ID50 15 and 40 nmol.kg-1, respectively; P < 0.01).

380636-50-0 (fumarate)

207679-81-0 (free base)

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