IC87114
- Catalog NO.:A19400
- CAS No. : 371242-69-2
- Molecular Formula:C22H19N7O
- Molecular Weight: 397.43
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 371242-69-2 | Appearance | Light yellow solid |
Catalog Number | A19400 | MDL Number | MFCD09970845 |
Molecular Formula | C22H19N7O | Molecular Weight | 397.43 |
Boiling Point | 673.681°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
IC-87114 is a potent and ATP-competitive PI3K p110δ isoform-selective inhibitor (IC50 = 60 nM). It Inhibits p110α, p110β and p110γ only at much higher concentrations. It does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100 µM. |