For R&D use only.

Telotristat ethyl

  • Catalog NO.:A853008
  • CAS No. : 1033805-22-9
  • Molecular Formula:C25H22ClF3N6O3
  • Molecular Weight: 546.93
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Product Details

CAS Number 1033805-22-9 Appearance
Catalog Number A853008 MDL Number MFCD18251583
Molecular Formula C25H22ClF3N6O3 Molecular Weight 546.93
Boiling Point Melting Point
Flash Point Density
Synonyms ethyl (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate;LX1606
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

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Signal Word Warning UN Number
Hazard Statements Class
Precautionary Statements Packing Group

Description

Telotristat ethyl, also known as LX 1032 or LX 1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor . Telotristat etiprate has activity in controlling diarrhea associated with carcinoid syndrome. LX1606 acts by inhibiting the enzyme tryptophan hydoxylase (TPH) and reduces serotonin production both inside and outside the GI tract without affecting brain serotonin levels. TPH is the rate-limiting enzyme involved in serotonin biosynthesis and is present in metastatic carcinoid tumor cells.

1137608-69-5 (etiprate)

1033805-22-9 (ethyl)

1033805-28-5 (acid)

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Telotristat ethyl
ethyl (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate;LX1606