KB-R7943
- Catalog NO.:A904111
- CAS No. : 182004-64-4
- Molecular Formula:C16H17N3O3S
- Molecular Weight: 331.39
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 182004-64-4 | Appearance | |
Catalog Number | A904111 | MDL Number | |
Molecular Formula | C16H17N3O3S | Molecular Weight | 331.39 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
KB-R7943 is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). KB-R7943 does not modify secondary pathology in the thalamus following focal cerebral stroke in rats. KB-R7943 blocks opening of the mitochondrial permeability transition pore. KB-R7943 restores endothelium-dependent relaxation induced by advanced glycosylation end products in rat aorta. KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion. |