PIK-75
- Catalog NO.:A874143
- CAS No. : 372196-67-3
- Molecular Formula:C16H14BrN5O4S
- Molecular Weight: 452.28
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 372196-67-3 | Appearance | |
Catalog Number | A874143 | MDL Number | MFCD12407411 |
Molecular Formula | C16H14BrN5O4S | Molecular Weight | 452.28 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | (E)-N'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models. |