NU7026
- Catalog NO.:A883723
- CAS No. : 154447-35-5
- Molecular Formula:C17H15NO3
- Molecular Weight: 281.31
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 154447-35-5 | Appearance | |
Catalog Number | A883723 | MDL Number | MFCD06798345 |
Molecular Formula | C17H15NO3 | Molecular Weight | 281.31 |
Boiling Point | 459.879°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | 2-morpholino-4H-benzo[h]chromen-4-one | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC50 values are 0.23, 13.0, > 100 and > 100 μM for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair. |