Enzastaurin
- Catalog NO.:A811194
- CAS No. : 170364-57-5
- Molecular Formula:C32H29N5O2
- Molecular Weight: 515.61
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 170364-57-5 | Appearance | White powder |
Catalog Number | A811194 | MDL Number | MFCD11040980 |
Molecular Formula | C32H29N5O2 | Molecular Weight | 515.61 |
Boiling Point | 767.2°C at 760 mmHg | Melting Point | 249-261℃ |
Flash Point | 417.8℃ | Density | |
Synonyms | 3-(1-methylindol-3-yl)-4-[1-[1-(2-pyridylmethyl)-4-piperidyl]-3a,7a-dihydroindol-3-yl]pyrrole-2,5-dione | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H412 | Class | |
Precautionary Statements | P273 | Packing Group |
Description
Potent PKCβ inhibitor (IC50 values are 6, 39, 83 and 110 nM for PKCβ, PKCα, PKCγ and PKCε, respectively). Suppresses proliferation and induces apoptosis in HCT116 colon carcinoma and U87MG glioblastoma cells in vitro. Reduces tumor growth and exhibits antiangiogenic activity in HT-29 colon carcinoma xenografts in mice. Also suppresses growth of HCT116 and U87MG xenografts in mice. Orally active. |