Belinostat
- Catalog NO.:A25012
- CAS No. : 414864-00-9
- Molecular Formula:C15H14N2O4S
- Molecular Weight: 318.35
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 414864-00-9 | Appearance | White solid |
Catalog Number | A25012 | MDL Number | MFCD08064035 |
Molecular Formula | C15H14N2O4S | Molecular Weight | 318.35 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | PXD101;N-Hydroxy-3-[3-[(Phenylamino)Sulfonyl]Phenyl]-2-Propenamide;Belinostat(Random Configuration) | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
A potent histone deacetylase (HDAC) activity inhibitor. It inhibits HDAC activity in HeLa cell extracts with an IC₅₀ of 27 nM. Belinostat significantly increases acetylation of histones H3 and H4 and potently inhibits the growth of prostate cancer cell lines (IC₅₀ range from 0.5 to 2.5 µM) with cytotoxic activity preferentially against tumor cells. |