Perifosine
- Catalog NO.:A23834
- CAS No. : 157716-52-4
- Molecular Formula:C25H52NO4P
- Molecular Weight: 461.66
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 157716-52-4 | Appearance | White to off-white solid |
Catalog Number | A23834 | MDL Number | MFCD00927554 |
Molecular Formula | C25H52NO4P | Molecular Weight | 461.66 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | (1,1-Dimethylpiperidin-1-ium-4-yl) octadecyl phosphate | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine. |