Aegelin
- Catalog NO.:A854351
- CAS No. : 456-12-2
- Molecular Formula:C18H19NO3
- Molecular Weight: 297.35
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Product Details
CAS Number | 456-12-2 | Appearance | |
Catalog Number | A854351 | MDL Number | MFCD00048045 |
Molecular Formula | C18H19NO3 | Molecular Weight | 297.35 |
Boiling Point | 567.6℃ at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl-2-propenamide;N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]cinnamamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H332-H335 | Class | |
Precautionary Statements | P261-P280-P305+P351+P338 | Packing Group |
Description
Aegeline is a main alkaloid isolated from Aegle marmelos Correa collected in Yogyakarta Indonesia. Aegeline inhibited the histamine release from RBL-2H3 cells induced by DNP(24)-BSA. Aegeline showed strong inhibition when RBL-2H3 cells induced by Ca(2+) stimulants such as thapsigargin and ionomycin. Tthe inhibitory effects of aegeline on the histamine release from mast cells depended on the type of mast cell and also involved some mechanisms related to intracellular Ca(2+) signaling events via the same target of the action of thapsigargin or downstream process of intracellular Ca(2+) signaling in mast cells. |