Pacritinib
- Catalog NO.:A856343
- CAS No. : 937272-79-2
- Molecular Formula:C28H32N4O3
- Molecular Weight: 472.58
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 937272-79-2 | Appearance | Crystalline solid |
Catalog Number | A856343 | MDL Number | MFCD22572772 |
Molecular Formula | C28H32N4O3 | Molecular Weight | 472.58 |
Boiling Point | 694.3±65.0°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | (16E)-11-[2-(1-Pyrrolidinyl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H317 | Class | |
Precautionary Statements | P280 | Packing Group |
Description
A potent JAK2/FLT3 inhibitor. Displays equipotent activity against JAK2 (I₅₀ = 23 nM) and FLT3 (IC₅₀ = 22 nM). SB1518 displays potent anti-proliferative effects on myeloid and lymphoid cell lines driven by mutant or wild-type JAK2 or FLT3, resulting from cell cycle arrest and induction of apoptosis. |