RVX-208
- Catalog NO.:A896210
- CAS No. : 1044870-39-4
- Molecular Formula:C20H22N2O5
- Molecular Weight: 370.40
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 1044870-39-4 | Appearance | Off-white powder |
Catalog Number | A896210 | MDL Number | MFCD18633270 |
Molecular Formula | C20H22N2O5 | Molecular Weight | 370.40 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | Apabetalone;2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H332-H335 | Class | |
Precautionary Statements | P261-P280-P305+P351+P338 | Packing Group |
Description
Apabetalone, also known as RVX-208, is a potent inhibitor of BET bromodomains. RVX-208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX-208 increases the production of ApoA-I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL-C, but the molecular target was not previously reported. RVX-208 may be a promising new approach to the treatment of atherosclerosis. |