Erlotinib hydrochloride

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For R&D use only.

Catalog NO.：A812763
CAS No. : 183319-69-9
Molecular Formula：C₂₂H₂₄ClN₃O₄
Molecular Weight： 429.9

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	183319-69-9	Appearance	White powder
Catalog Number	A812763	MDL Number	MFCD07781272
Molecular Formula	C₂₂H₂₄ClN₃O₄	Molecular Weight	429.9
Boiling Point		Melting Point	228-235°C
Flash Point		Density
Synonyms	N-(4-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride;Erlotinib HCl (OSI-744)
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number	Not hazmat
Hazard Statements	H315; H319; H335	Class
Precautionary Statements	P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501	Packing Group

Description

Erlotinib hydrochloride is the hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.

183319-69-9 (HCl)

183321-74-6 (free base)

248594-19-6 (mesylaye)

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