PF-8380
- Catalog NO.:A894200
- CAS No. : 1144035-53-9
- Molecular Formula:C22H21Cl2N3O5
- Molecular Weight: 478.33
Note*
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1144035-53-9 | Appearance | Light brown powder |
Catalog Number | A894200 | MDL Number | MFCD20527274 |
Molecular Formula | C22H21Cl2N3O5 | Molecular Weight | 478.33 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 3,5-Dichlorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335-H413 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Potent autotaxin inhibitor (IC50 = 2.8 nM in isolated enzyme assay; 101 nM in human whole blood). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at site of inflammation. Decreases leptin-induced MMP13 expression, in vitro. Orally available. |