For R&D use only.

Daclatasvir dihydrochloride

  • Catalog NO.:A850925
  • CAS No. : 1009119-65-6
  • Molecular Formula:C40H52Cl2N8O6
  • Molecular Weight: 811.81
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Product Details

CAS Number 1009119-65-6 Appearance Off-white powder
Catalog Number A850925 MDL Number MFCD25541736
Molecular Formula C40H52Cl2N8O6 Molecular Weight 811.81
Boiling Point Melting Point
Flash Point Density
Synonyms methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate dihydrochloride
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H317 Class
Precautionary Statements P280 Packing Group

Description

Daclatasvir (USAN), also known as BMS-790052 and EBP-883 (trade name Daklinza), is NS5A inhibitor and a drug for the treatment of hepatitis C (HCV). It is was developed by Bristol-Myers Squibb and was approved in Europe on 22 August 2014. Daclatasvir inhibits the HCV nonstructural protein NS5A. Recent research suggests that it targets two steps of the viral replication process, enabling rapid decline of HCV RNA. Daclatasvir has been tested in combination regimens with pegylated interferon and ribavirin, as well as with other direct-acting antiviral agents including asunaprevir and sofosbuvir.

1009119-65-6 (2HCl salt)

1009119-64-5 (free base)

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Daclatasvir dihydrochloride
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]phenyl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate dihydrochloride