For R&D use only.

Binimetinib

  • Catalog NO.:A857417
  • CAS No. : 606143-89-9
  • Molecular Formula:C17H15BrF2N4O3
  • Molecular Weight: 441.23
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 606143-89-9 Appearance White powder
Catalog Number A857417 MDL Number MFCD22124525
Molecular Formula C17H15BrF2N4O3 Molecular Weight 441.23
Boiling Point Melting Point
Flash Point Density
Synonyms MEK 162; ARRY162;5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;ARRY-162
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

Binimetinib, also known as MEK162 (ARRY-162), is an oral, highly selective MEK inhibitor. In preclinical studies, MEK162 showed significant antitumor activities in cell lines and animal models. MEK162 is the first targeted therapy to show activity in patients with NRAS -mutated melanoma and might offer a new option for a cancer with few effective treatments.

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Binimetinib
MEK 162; ARRY162;5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;ARRY-162