MLN2480
- Catalog NO.:A894984
- CAS No. : 1096708-71-2
- Molecular Formula:C17H12Cl2F3N7O2S
- Molecular Weight: 506.29
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
COA
Product Details
CAS Number | 1096708-71-2 | Appearance | |
Catalog Number | A894984 | MDL Number | MFCD22571730 |
Molecular Formula | C17H12Cl2F3N7O2S | Molecular Weight | 506.29 |
Boiling Point | 585.3±50.0°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | TAK580;MLN 2480;MLN-2480;(R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-Raf kinase inhibitor. The Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival within the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf. |