Nexturastat A
- Catalog NO.:A858210
- CAS No. : 1403783-31-2
- Molecular Formula:C19H23N3O3
- Molecular Weight: 341.40
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1403783-31-2 | Appearance | |
Catalog Number | A858210 | MDL Number | MFCD28099804 |
Molecular Formula | C19H23N3O3 | Molecular Weight | 341.40 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50= 5.02 +/- 0.60 nM). Nexturastat A possesses antiproliferative effects against melanoma cells. Histone deacetylases (HDACs) mediate regulation of gene expression via changes in nucleosome conformation. Dysregulation of histone acetylation can lead to the development of cancers. There is renewed interest in capitalizing new breakthroughs in epigenetic research to address oncology therapy. |