MBX 2982
- Catalog NO.:A852666
- CAS No. : 1037792-44-1
- Molecular Formula:C22H24N8Os
- Molecular Weight: 448.54
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Product Details
CAS Number | 1037792-44-1 | Appearance | |
Catalog Number | A852666 | MDL Number | MFCD22628771 |
Molecular Formula | C22H24N8Os | Molecular Weight | 448.54 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | SAR-260093;5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine;MBX-2982 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H317-H319 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
MBX-2982, also known as SAR-260093, is a potential first-in-class treatment for type 2 diabetes that targets G protein-coupled receptor 119 (GPR119), a receptor that interacts with bioactive lipids known to stimulate glucose-dependent insulin secretion. Preclinical data indicate that MBX-2982 is a potent selective orally-active GPR119 agonist that functions through a unique dual mechanism of action. First, it acts directly on the beta cell to increase insulin secretion. In addition, MBX-2982 stimulates release of the incretin GLP-1 from the gut. This dual action is unique and may offer improved glucose homeostasis over existing diabetes therapies, with potential for weight loss and improved islet health. |