ML-7 HCl
- Catalog NO.:A802196
- CAS No. : 110448-33-4
- Molecular Formula:C15H18CliN2O2S
- Molecular Weight: 452.74
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 110448-33-4 | Appearance | |
Catalog Number | A802196 | MDL Number | MFCD00065524 |
Molecular Formula | C15H18CliN2O2S | Molecular Weight | 452.74 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 1-[(5-iodo-1-naphthyl)sulfonyl]-1,4-diazepane hydrochloride;ML-7 hydrochloride | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
ML-7 is a MLCK inhibitor. ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM. ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line. ML-7 inhibits exocytosis of superoxide-producing intracellular compartments in human neutrophils stimulated with phorbol myristate acetate in a myosin light chain kinase-independent manner. |