Lasmiditan
- Catalog NO.:A857750
- CAS No. : 439239-90-4
- Molecular Formula:C19H18F3N3O2
- Molecular Weight: 377.36
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 439239-90-4 | Appearance | |
Catalog Number | A857750 | MDL Number | MFCD18633238 |
Molecular Formula | C19H18F3N3O2 | Molecular Weight | 377.36 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | COL 144; 2,4,6-Trifluoro-N-[6-[(1-methyl-4-piperidinyl)carbonyl]-2-pyridinyl]benzamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo. |