BP897
- Catalog NO.:A875893
- CAS No. : 314776-92-6
- Molecular Formula:C26H32ClN3O2
- Molecular Weight: 454.00
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 314776-92-6 | Appearance | |
Catalog Number | A875893 | MDL Number | MFCD04039996 |
Molecular Formula | C26H32ClN3O2 | Molecular Weight | 454.00 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
BP897 is a potent (K(i) = 0.92 nM) dopamine D(3) receptor compound developed for the treatment of cocaine abuse and craving. BP 897 has a high selectivity for the dopamine D(3) versus D(2) receptors (70-fold) and a moderate affinity for 5-HT(1A) receptors, (K(i) = 84 nM), adrenergic-alpha(1) (K(i) = 60 nM) and -alpha(2) adrenoceptors (K(i) = 83 nM). BP 897 displays significant intrinsic activity at the human dopamine D(3) receptor by decreasing forskolin-stimulated cAMP levels and by stimulating mitogenesis of dopamine D(3)-expressing NG108-15 cells. |