For R&D use only.

BP897

  • Catalog NO.:A875893
  • CAS No. : 314776-92-6
  • Molecular Formula:C26H32ClN3O2
  • Molecular Weight: 454.00
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Product Details

CAS Number 314776-92-6 Appearance
Catalog Number A875893 MDL Number MFCD04039996
Molecular Formula C26H32ClN3O2 Molecular Weight 454.00
Boiling Point Melting Point
Flash Point Density
Synonyms N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

BP897 is a potent (K(i) = 0.92 nM) dopamine D(3) receptor compound developed for the treatment of cocaine abuse and craving. BP 897 has a high selectivity for the dopamine D(3) versus D(2) receptors (70-fold) and a moderate affinity for 5-HT(1A) receptors, (K(i) = 84 nM), adrenergic-alpha(1) (K(i) = 60 nM) and -alpha(2) adrenoceptors (K(i) = 83 nM). BP 897 displays significant intrinsic activity at the human dopamine D(3) receptor by decreasing forskolin-stimulated cAMP levels and by stimulating mitogenesis of dopamine D(3)-expressing NG108-15 cells.

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BP897
N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide