Fostamatinib disodium

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For R&D use only.

Catalog NO.：A896768
CAS No. : 1025687-58-4
Molecular Formula：C₂₃H₂₄FN₆Na₂O₉P
Molecular Weight： 624.42

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	1025687-58-4	Appearance	White powder
Catalog Number	A896768	MDL Number	MFCD15146370
Molecular Formula	C₂₃H₂₄FN₆Na₂O₉P	Molecular Weight	624.42
Boiling Point		Melting Point
Flash Point		Density
Synonyms	6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one sodium salt;R788 Disodium
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage.

1025687-58-4 (sodium)

901119-35-5 (free acid)

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