DAPT
- Catalog NO.:A25152
- CAS No. : 208255-80-5
- Molecular Formula:C23H26F2N2O4
- Molecular Weight: 432.46
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 208255-80-5 | Appearance | |
Catalog Number | A25152 | MDL Number | MFCD04974585 |
Molecular Formula | C23H26F2N2O4 | Molecular Weight | 432.46 |
Boiling Point | 612.2°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | (S)-tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate;LY-374973 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Inhibitor of γ-secretase; causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo. Does not affect APPα and APPβ levels. Blocks Notch signaling in hybrid human-mouse fetal thymus organ culture (FTOC). Activity causes ESCs to commit to neuronal differentiation. |