Dorsomorphin
- Catalog NO.:A841757
- CAS No. : 866405-64-3
- Molecular Formula:C24H25N5O
- Molecular Weight: 399.49
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 866405-64-3 | Appearance | |
Catalog Number | A841757 | MDL Number | MFCD08705402 |
Molecular Formula | C24H25N5O | Molecular Weight | 399.49 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | BML-275; 6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H312-H332 | Class | |
Precautionary Statements | P280 | Packing Group |
Description
Cell-permeable. A potent, selective , reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM in the presence of 5 µM ATP and no AMP). Does not affect the activity on several structurally related kinases including JAK3, PKA, PKCθ, SYK and ZAPK. Also inhibits bone morphogenic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). In addition, recently Dorsomorphin has shown to induce protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. |