Pictilisib mesylate

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For R&D use only.

Catalog NO.：A858922
CAS No. : 957054-33-0
Molecular Formula：C₂₅H₃₅N₇O₉S₄
Molecular Weight： 705.85

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Product Details

CAS Number	957054-33-0	Appearance
Catalog Number	A858922	MDL Number
Molecular Formula	C₂₅H₃₅N₇O₉S₄	Molecular Weight	705.85
Boiling Point		Melting Point
Flash Point		Density
Synonyms	4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine dimesylate;GDC-0941 dimethanesulfonate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity. PI3K inhibitor GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result.

957054-30-7 (free base)

957054-33-0 (mesylate)

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