Pyridostatin HCl

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For R&D use only.

Catalog NO.：A904069
CAS No. : 1629261-49-9
Molecular Formula：C₃₁H₃₃ClN₈O₅
Molecular Weight： 633.11

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Product Details

CAS Number	1629261-49-9	Appearance
Catalog Number	A904069	MDL Number
Molecular Formula	C₃₁H₃₃ClN₈O₅	Molecular Weight	633.11
Boiling Point		Melting Point
Flash Point		Density
Synonyms	4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide HCl
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage response by causing the formation of DNA double strand breaks (DSB). Pyridostatin promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin targets gene bodies containing clusters of sequences with a propensity for G-quadruplex formation. As a result, pyridostatin modulated the expression of these genes, including the proto-oncogene SRC.

1472611-44-1 (TFA)

1085412-37-8 (free base)

1629261-49-9 (HCl)

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