Amonafide L-malate

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For R&D use only.

Catalog NO.：A903950
CAS No. : 618863-54-0
Molecular Formula：C₂₀H₂₃N₃O₇
Molecular Weight： 417.42

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Product Details

CAS Number	618863-54-0	Appearance
Catalog Number	A903950	MDL Number
Molecular Formula	C₂₀H₂₃N₃O₇	Molecular Weight	417.42
Boiling Point		Melting Point
Flash Point		Density
Synonyms	5-amino-2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione L-malate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Amonafide L-malate is the malate salt of amonafide, an imide derivative of naphthalic acid, with potential antineoplastic activity. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in DNA double-strand breaks (DSB) and inhibition of DNA replication and RNA synthesis.

69408-81-7 (free base)

150091-68-2 (2HCl)

618863-54-0 (malate)

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