ML 161
- Catalog NO.:A872901
- CAS No. : 423735-93-7
- Molecular Formula:C17H17BrN2O2
- Molecular Weight: 361.24
Note*
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3. The price does not include shipping and bank charges.
Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 423735-93-7 | Appearance | Brown powder |
Catalog Number | A872901 | MDL Number | MFCD03063772 |
Molecular Formula | C17H17BrN2O2 | Molecular Weight | 361.24 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 2-Bromo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | 3077 |
Hazard Statements | H302-H315-H319-H335 | Class | 9 |
Precautionary Statements | P261-P305+P351+P338 | Packing Group | III |
Description
ML-161 is a potent and reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 µM. ML161 inhibited platelet aggregation induced by a PAR1 peptide agonist or by thrombin but not by several other platelet agonists. Initial studies suggest that ML161 is an allosteric inhibitor of PAR1. These findings may be important for the discovery of antithrombotics with an improved safety profile. |