RS 102895 hydrochloride

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For R&D use only.

Catalog NO.：A893398
CAS No. : 1173022-16-6
Molecular Formula：C₂₁H₂₂ClF₃N₂O₂
Molecular Weight： 426.86

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Quality Control&SDS

Product Details

CAS Number	1173022-16-6	Appearance
Catalog Number	A893398	MDL Number	MFCD08703093
Molecular Formula	C₂₁H₂₂ClF₃N₂O₂	Molecular Weight	426.86
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

RS-102895 HCl is a CCR2-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). RS-102895 HCl blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. It also inhibits α1A, α1D and 5-HT1A receptors.

1173022-16-6 (RS-102895 HCl)

300815-41-2(RS-102895)

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