Uridine-5'-triphosphoric acid trisodium salt

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Catalog NO.：A813966
CAS No. : 19817-92-6
Molecular Formula：C₉H₁₂N₂Na₃O₁₅P₃
Molecular Weight： 550.09

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	19817-92-6	Appearance	White powder
Catalog Number	A813966	MDL Number	MFCD00044310
Molecular Formula	C₉H₁₂N₂Na₃O₁₅P₃	Molecular Weight	550.09
Boiling Point		Melting Point
Flash Point		Density
Synonyms	sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate;UTP Na3;URIDINE-5'- TRIPHOSPHATE, TRISODIUM SALT
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H315;H317;H319;H335;H360	Class
Precautionary Statements	P201;P261;P280;P305+P351+P338;P308+P313	Packing Group

Description

Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore.

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