GNE 7915
- Catalog NO.:A858153
- CAS No. : 1351761-44-8
- Molecular Formula:C19H21F4N5O3
- Molecular Weight: 443.40
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1351761-44-8 | Appearance | |
Catalog Number | A858153 | MDL Number | MFCD25977005 |
Molecular Formula | C19H21F4N5O3 | Molecular Weight | 443.40 |
Boiling Point | 629.9±65.0°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | (4-((4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-fluoro-5-methoxyphenyl)(morpholino)methanone;GNE-7915 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
GNE-7915 is a potent LRRK2 kinase inhibitor, which possess an ideal balance of LRRK2 cellular potency, broad kinase selectivity, metabolic stability, and brain penetration across multiple species. GNE-7915 was reported as a potent (IC50=9 nM) selective (1/187 kinases), brain-penetrant and non-toxic inhibitor of LRRK2. |