LXR-623
- Catalog NO.:A862519
- CAS No. : 875787-07-8
- Molecular Formula:C21H12ClF5N2
- Molecular Weight: 422.78
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 875787-07-8 | Appearance | |
Catalog Number | A862519 | MDL Number | MFCD16495812 |
Molecular Formula | C21H12ClF5N2 | Molecular Weight | 422.78 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | WAY 252623;2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H301 | Class | |
Precautionary Statements | P301+P310 | Packing Group |
Description
Potent LXR agonist (IC50 values are 24 and 179 nM for LXRβ and LXRα, respectively). Reduces total serum cholesterol and LDL cholesterol, and inhibits lesion growth in models of atherosclerosis. Increases ABCA1 and ABCG1 mRNA levels in rat peripheral blood cells. Orally bioavailable. |