PF 04217903 mesylate

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For R&D use only.

Catalog NO.：A25466
CAS No. : 956906-93-7
Molecular Formula：C₂₀H₂₀N₈O₄S
Molecular Weight： 468.49

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Product Details

CAS Number	956906-93-7	Appearance
Catalog Number	A25466	MDL Number
Molecular Formula	C₂₀H₂₀N₈O₄S	Molecular Weight	468.49
Boiling Point		Melting Point
Flash Point		Density
Synonyms	2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol mesylate;PF-04217903 methanesulfonate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

PF-04217903 is a MET tyrosine kinase inhibitor, is also a n orally bioavailabe, small-molecule tyrosine kinase inhibitor of the proto-oncogene c-Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor PF-04217903 selectively binds to and inhibits c-Met, disrupting the c-Met signaling pathway, which may result in the inhibition of tumor cell growth, migration and invasion of tumor cells, and the induction of death in tumor cells expressing c-Met.

956905-27-4 (free base)

956906-93-7 (mesylate)

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P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
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