For R&D use only.

2-(3-(4-Hydroxyphenyl)propanamido)benzoic acid

  • Catalog NO.:A930262
  • CAS No. : 697235-49-7
  • Molecular Formula:C16H15NO4
  • Molecular Weight: 285.29
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 697235-49-7 Appearance Off-white powder
Catalog Number A930262 MDL Number
Molecular Formula C16H15NO4 Molecular Weight 285.29
Boiling Point 590.0±40.0 °C Melting Point
Flash Point Density 1.354±0.06 g/cm3
Synonyms 2-(3-(4-Hydroxyphenyl)propanamido)benzoic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group

Description

Dinaciclib, also known as SCH727965, is a potent CDK inhibitor with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC(50) values of 1, 1, 3, and 4 nmol/L, respectively. Compared with flavopiridol, Dinaciclib exhibits superior activity with an improved therapeutic index. Dinaciclib induced regression of established solid tumors in a range of mouse models following intermittent scheduling of doses below the maximally tolerated level.

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2-(3-(4-Hydroxyphenyl)propanamido)benzoic acid
2-(3-(4-Hydroxyphenyl)propanamido)benzoic acid