For R&D use only.

Isorhoifolin

  • Catalog NO.:A934695
  • CAS No. : 552-57-8
  • Molecular Formula:C27H30O14
  • Molecular Weight: 578.52
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Product Details

CAS Number 552-57-8 Appearance
Catalog Number A934695 MDL Number
Molecular Formula C27H30O14 Molecular Weight 578.52
Boiling Point 912.7°C at 760 mmHg Melting Point 270-275oC
Flash Point 304.1oC Density 1.69g/cm3
Synonyms 4',5-Dihydroxy-7-[6-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]flavone
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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Isorhoifolin
4',5-Dihydroxy-7-[6-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]flavone