For R&D use only.

(3-Amino-2,4-difluorophenyl)-[5-bromo-1-(2,6-dichlorobenzoyl)pyrrolo[2,3-b]pyridin-3-yl]methanone

  • Catalog NO.:A939002
  • CAS No. : 2409141-17-7
  • Molecular Formula:C21H10BrCl2F2N3O2
  • Molecular Weight: 525.13
Note*
1. Please click the  to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Bulk Inquiry
Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 2409141-17-7 Appearance Off-white to light yellow powder
Catalog Number A939002 MDL Number
Molecular Formula C21H10BrCl2F2N3O2 Molecular Weight 525.13
Boiling Point Melting Point
Flash Point Density
Synonyms (3-Amino-2,4-difluorophenyl)-[5-bromo-1-(2,6-dichlorobenzoyl)pyrrolo[2,3-b]pyridin-3-yl]methanone
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group

Description

Bafilomycin A1, also known as NSC 381866, is a selective, reversible inhibitor of vacuolar H+-ATPases (V-ATPases), blocking these proton pumps in mammalian, plant, or fungal cells with an IC50 value in the 4-400 nM range. Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice. Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways.

Related Products

Batch search Close
Batch processing can be done by CAS number, CAS number, one search per line
...

(3-Amino-2,4-difluorophenyl)-[5-bromo-1-(2,6-dichlorobenzoyl)pyrrolo[2,3-b]pyridin-3-yl]methanone
(3-Amino-2,4-difluorophenyl)-[5-bromo-1-(2,6-dichlorobenzoyl)pyrrolo[2,3-b]pyridin-3-yl]methanone