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Cupric citrate

  • Catalog NO.:A947384
  • CAS No. : 10402-15-0
  • Molecular Formula:C6H5Cu2O7
  • Molecular Weight: 316.19
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Product Details

CAS Number 10402-15-0 Appearance
Catalog Number A947384 MDL Number
Molecular Formula C6H5Cu2O7 Molecular Weight 316.19
Boiling Point Melting Point
Flash Point Density
Synonyms Cupric citrate
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

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Signal Word Warning UN Number
Hazard Statements Class
Precautionary Statements Packing Group

Description

Palbociclib, also known as PD-0332991, is an orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. This suppresses DNA replication and decreases tumor cell proliferation. CDK4 and 6 are serine/threonine kinases that are upregulated in many tumor cell types and play a key role in the regulation of cell cycle progression. Palbociclib, was approved on February 3, 2015 as a treatment (in combination with letrozole) for patients with estrogen receptor-positive advanced breast cancer.

571190-30-2 (free base)

827022-32-2 (HCl)

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Cupric citrate
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