Ethynyl Estradiol
- Catalog NO.:A949437
- CAS No. : 57-63-6
- Molecular Formula:C20H24O2
- Molecular Weight: 296.40
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Product Details
CAS Number | 57-63-6 | Appearance | |
Catalog Number | A949437 | MDL Number | MFCD00003690 |
Molecular Formula | C20H24O2 | Molecular Weight | 296.40 |
Boiling Point | 378°C | Melting Point | 180-188°C |
Flash Point | Density | ||
Synonyms | (8R,9S,13S,14S,17R)-17-Ethynyl-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | Not hazmat |
Hazard Statements | H302;H315;H319;H335 | Class | |
Precautionary Statements | P261;P305+P351+P338 | Packing Group |
Description
PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. Check for active clinical trials or closed clinical trials using this agent. |