[1,1'-Biphenyl]-2,5-dicarboxylic acid

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For R&D use only.

Catalog NO.：A826581
CAS No. : 4445-51-6
Molecular Formula：C₁₄H₁₀O₄
Molecular Weight： 242.23

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	4445-51-6	Appearance	White solid
Catalog Number	A826581	MDL Number
Molecular Formula	C₁₄H₁₀O₄	Molecular Weight	242.23
Boiling Point		Melting Point
Flash Point		Density
Synonyms	2-Phenyl-1,4-benzenedicarboxylic acid; 2-Phenylterephthalic acid; Phenylterephthalic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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