N1,N1'-(1,4-Phenylene)bis(N1-(4-aminophenyl)benzene-1,4-diamine)
- Catalog NO.：A847420
- CAS No. : 3283-07-6
- Molecular Formula：C30H28N6
- Molecular Weight： 472.58
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Product Details
| CAS Number | 3283-07-6 | Appearance | Dark green powder |
| Catalog Number | A847420 | MDL Number | MFCD06657652 |
| Molecular Formula | C30H28N6 | Molecular Weight | 472.58 |
| Boiling Point | 765.6°C at 760 mmHg | Melting Point | |
| Flash Point | Density | ||
| Synonyms | N1,N1'-(1,4-Phenylene)bis(N1-(4-aminophenyl)benzene-1,4-diamine) | ||
| Storage Condition | Store in a tightly closed container,in a cool and dry place | ||
Safety
| GHS Pictogram |
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| Signal Word | Warning | UN Number | |
| Hazard Statements | H302 | Class | |
| Precautionary Statements | P280-P305+P351+P338 | Packing Group | |
Description
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Ivacaftor, also known as VX-770, is a drug used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis, and is included in a combination drug, lumacaftor/ivacaftor, which is used to treat people with cystic fibrosis who have the F508del mutation in CFTR. Ivacaftor is a "potentiator" of CFTR, meaning it increases the probability that the defective channel will be open and allow chloride ions pass through the channel pore. |
