For R&D use only.

3,4-Difluropyridine

  • Catalog NO.:A850855
  • CAS No. : 82878-63-5
  • Molecular Formula:C5H3F2N
  • Molecular Weight: 115.08
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SDS COA HPLC/GC NMR

Product Details

CAS Number 82878-63-5 Appearance Light yellow liquid
Catalog Number A850855 MDL Number MFCD04114246
Molecular Formula C5H3F2N Molecular Weight 115.08
Boiling Point 105.3°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 3,4-Difluropyridine
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 1993
Hazard Statements H226-H315-H319-H335 Class 3
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87-2243 mproves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment. BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0.037). Additional BAY-87-2243 application during RT did not decrease TCD50.

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3,4-Difluropyridine
3,4-Difluropyridine